持续性疼痛是转移性肿瘤的常见症状,而在那些有肿瘤脊柱转移的患者中疼痛与脊柱不稳有关。任何肿瘤均能转移到脊柱而产生足量的骨质破坏,从而导致脊柱不稳,脊髓机械不稳可导致持续剧痛,并可引起脊髓神经压迫,从而导致区域性麻痹。X线平片可显示椎体轻度至完全的病理性压缩骨折,跳跃式压缩骨折并不常见。椎体的骨质破坏与附件的病理骨折同样重要,因为疼痛是由于病理骨折引起的脊柱机械性不稳定所致,而非肿瘤转移本身。放疗及化疗虽然可能对控制肿瘤生长有效,但对缓解疼痛无效。与治疗长 Persistent pain is a common symptom of metastatic tumors, and in those with spinal metastases, pain is associated with instability of the spine. Any tumor can metastasize to the spine and produce a sufficient amount of bone destruction, leading to instability of the spine. Mechanical instability of the spinal cord can lead to continued severe pain and can cause spinal nerve compression, leading to regional paralysis. X-ray film can show mild to complete pathological compression fractures of the vertebral body. Jump compression fractures are not common. The bone destruction of the vertebral body is just as important as the pathological fracture of the accessory, because the pain is due to the mechanical instability of the spine caused by the pathological fracture, not the tumor metastasis itself. Although radiotherapy and chemotherapy may be effective in controlling tumor growth, it is not effective in relieving pain. And treatment