碳酸酐酶抑制剂不仅可用于降低青光眼病人的眼压,同时还有抗惊厥和利尿作用。虽然这些药物能产生明显的全身副作用,但最严重的副作用是再生障碍性贫血。以前,已报告过22例服用乙酰唑胺和甲醋唑胺后出现血液的变化,另外,有57例病人服用乙酰唑胺、甲醋唑胺和二氯酰胺后,出现了血液的不良反应,这些病例已向“药物引起眼副作用国家登记处”作了报告。 Carbonic anhydrase inhibitors not only can be used to reduce glaucoma in patients with intraocular pressure, as well as anticonvulsant and diuretic effects. Although these drugs can produce significant systemic side effects, the most serious side effect is aplastic anemia. In the past 22 blood transfusions of acetazolamide and metformin have been reported. In addition, 57 patients had adverse reactions to blood following administration of acetazolamide, metformin and dichloroamide, These cases have been reported to the National Registry for Eye-Side Effects of Drugs.