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例1,女,8个月,因发热,肌注安痛定1/3支,当天臀部、下肢出现淤点、淤斑,逐渐增多并扩大融合,第3天入院。查体T39℃,血压11.4/8.6kPa,精神萎靡,双下肢散在大片淤斑,右臀部、右大腿后内侧,右腹股沟区大片融合紫癜,周边鲜红,中央呈紫色,部分凹陷变硬。检验血常规、出凝血时间、脑脊液均正常,皮疹印片检菌阴性。7天后散在淤点淤斑开始消退,大片紫癜变为棕褐色,触之硬似皮革样,与正常皮肤分界清楚。入院后血培养与坏死区分泌物培养无菌生长。病理检查
Example 1, female, 8 months, due to fever, intramuscular injection of analgesic 1/3, the same day, the buttocks, lower extremities appear cramps, ecchymosis, and gradually increase and expand the fusion, the first 3 days admission. Physical examination T39 ℃, blood pressure 11.4 / 8.6kPa, apathetic, double lower extremity scattered large ecchymosis, right hip, the right posterior thigh, the right groin area merger purpura, the surrounding red, the central purple, partially sagged. Blood tests, a clotting time, cerebrospinal fluid were normal, rash imprint negative bacteria. Scattered spots scattered after 7 days began to subside, large purpura into brown, touch the hard leather-like, clear boundaries with normal skin. After admission, blood cultures and necrotic areas secreted aseptic growth. Pathological examination