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肿瘤的转移往往是肿瘤病人死亡的直接原因，转移受其自身的转移基因及转移抑制基因的调控，ｎｍ２３作为转移抑制基因定位于人体１７号染色体长臂（１７ｑ２２），编码产物为二磷酸核苷激酶（ＮＤＰＫ），具有肿瘤转移抑制潜能。ｎｍ２３－Ｈ１蛋白与乳腺癌等肿瘤转移的关...
Tumor metastasis is often the direct cause of death of cancer patients. Metastasis is regulated by its own metastasis genes and metastasis suppressor genes. nm23 is identified as a metastasis suppressor gene located on the long arm of human chromosome 17 (17q22), and the encoded product is a nucleoside diphosphate. Kinase (NDPK) has tumor metastasis suppressing potential. nm23-H1 protein and breast cancer and other tumor metastasis...