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目的通过对比分析阿奇霉素治疗前、后支原体肺炎患儿C-反应蛋白及心肌酶水平,探讨阿奇霉素在治疗小儿支原体肺炎中的疗效。方法以133例支原体肺炎患儿为研究对象,分为对照组66例和研究组67例。对照组采用常规的红霉素治疗,研究组采用阿奇霉素治疗,对比分析两组的治疗效果。结果研究组治疗有效率97.01%显著高于对照组83.33%,差异有统计学意义(P<0.05);两组在接受治疗后C-反应蛋白含量都下降显著,与治疗前比较差异有统计学意义(P<0.05);且研究组C-反应蛋白含量(6.6±0.8)mg/L显著低于对照组(16.2±1.1)mg/L,差异有统计学意义(P<0.05);两组在治疗后心肌酶谱各指标均下降显著,且与治疗前比较差异有统计学意义(P<0.05)。结论在治疗小儿支原体肺炎时阿奇霉素疗效显著,且可有效降低C-反应蛋白及心肌酶含量,减少支原体属感染后对心肌的损伤。
Objective To compare and analyze the levels of C-reactive protein and myocardial enzymes in children with mycoplasma pneumonia before and after azithromycin treatment, and to explore the effect of azithromycin in the treatment of children with mycoplasmal pneumonia. Methods A total of 133 children with mycoplasma pneumonia were divided into control group (66 cases) and study group (67 cases). Control group using conventional erythromycin treatment, the study group treated with azithromycin, comparative analysis of the two groups of treatment. Results The effective rate of treatment in study group was 97.01%, which was significantly higher than that in control group (83.33%), the difference was statistically significant (P <0.05). The C-reactive protein content of both groups dropped significantly after treatment, (P <0.05). The content of C-reactive protein in the study group (6.6 ± 0.8) mg / L was significantly lower than that in the control group (16.2 ± 1.1) mg / L After treatment, each index of myocardial enzymes decreased significantly, and compared with before treatment, the difference was statistically significant (P <0.05). Conclusion Azithromycin has a significant effect in the treatment of mycoplasma pneumonia in children, and can effectively reduce the content of C-reactive protein and myocardial enzymes and reduce the myocardial damage caused by Mycoplasma infection.