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脑血通口服液由天麻、钩藤、全瓜篓、鲜竹沥、赤芍、水蛭等中药组成,具有化痰熄风、祛瘀通络之功效,临床用于治疗缺血性脑血管病具有显著疗效。有研究表明,该品能明显改善脑缺血大鼠神经病学症状,缩小脑梗死面积,促进坏死灶内出血吸收和胶质细胞增生修复,减少周围区水肿和炎症反应。本文通过阻断大鼠一侧大脑中动脉造成局灶性脑缺血模型,进一步探讨脑血通口服液的作用机理。 实验材料
Naoxuetong Oral Liquid is composed of Tianma, Uncaria rhaponticum, Rhizoma mellonellae, Fresh bamboo lek, Radix paeoniae Rubra, and Radix Astragali and other traditional Chinese medicines. It has the effects of eliminating stasis, extinguishing wind, removing phlegm and collaterals, and is used clinically to treat ischemic cerebrovascular disease. Has a significant effect. Studies have shown that the product can significantly improve the neurological symptoms in rats with cerebral ischemia, reduce the area of cerebral infarction, promote necrotic lesions absorption of hemorrhage and glial cell proliferation repair, reduce the surrounding area edema and inflammation. This article further explored the mechanism of Naoxuetong oral liquid by blocking the middle cerebral artery of rats to create a model of focal cerebral ischemia. Experimental Materials