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目的:探讨药物流产后阴道出血的相关因素及流产后加服雌激素(补佳乐)、宫缩剂(益母草片)对阴道出血时间的影响。方法:选取102例临床诊断为宫内早孕、要求药物流产的妇女,测定药物流产前的孕囊直径及血β-HCG水平,流产后随机分为3组,A组给予益母草片,B组给予补佳乐,C组给予安慰剂,分析各组药物流产后阴道出血时间的差异及其与孕囊直径、血β-HCG水平的关系。结果:流产前的孕囊直径大小及血β-HCG水平与药物流产后阴道出血时间成正相关,流产后加服宫缩剂及雌激素皆可缩短阴道出血时间,但以雌激素效果更为显著(P<0.01)。结论:药物流产前的孕囊直径及血β-HCG水平影响药物流产后的阴道出血时间,流产后加服少量雌激素可明显缩短阴道出血时间。
Objective: To investigate the related factors of vaginal bleeding after medical abortion and the effect of adding estrogen (Bu Jiale) and uterotonics (motherwort tablets) on vaginal bleeding time after abortion. Methods: 102 women diagnosed as early pregnancy intrauterine pregnancy and requiring medical abortion were enrolled. The gestational sac diameter and blood β-HCG level were measured before abortion. After abortion, they were randomly divided into 3 groups: group A was given Motherwort tablets; group B was given The patients in group C were given placebo. The difference of vaginal bleeding time after medical abortion and the relationship between gestational sac diameter and blood β-HCG level were analyzed. Results: The size of the gestational sac and the blood β-HCG level before the abortion were positively correlated with the vaginal bleeding time after medical abortion. After abortion plus uterotonic and estrogen can shorten the vaginal bleeding time, but the estrogen effect is more significant (P <0.01). Conclusions: The gestational sac size and blood β-HCG level before medical abortion affect vaginal bleeding time after medical abortion. Adding a small amount of estrogen after abortion may shorten the vaginal bleeding time significantly.