论文部分内容阅读
近百年来,随着科学技术的发展和应用,对急性肾功能衰竭(ARF)的研究日益深入,认识不断提高。认为缺血性ARF的发病机制主要是1.肾血流量(RBF)减少,肾内皮一髓分流;2.滤过分数及肾小球滤过率(GFR)下降;3.肾小管上皮细胞坏死及小管液被动回漏;4.肾小管梗阻。近几年来,通过电镜技术、肾血管显影及分区测定RBF,发现肾缺血之后,外皮层血流量很快回升,接近正常水平。而髓旁肾单位血流量持续减少,同时外髓层血液瘀滞。这些发现基本上否定了多年来公认的肾内皮一髓分流的观点。本文就髓质血液循环的解剖学基
Over the past century, with the development and application of science and technology, the research on acute renal failure (ARF) has been deepened and the awareness has been continuously improved. It is considered that the pathogenesis of ischemic ARF is mainly 1. The reduction of renal blood flow (RBF), the myeloid degeneration of renal endothelium; 2. Filtration fraction and glomerular filtration rate (GFR) decreased; 3. Renal tubular epithelial cell necrosis And small tube fluid passive leakage; 4. Tubular obstruction. In recent years, electron microscopy, renal angiography and regional determination of RBF found that renal ischemia, the cortical blood flow quickly rose to close to normal levels. The parasellar nephron blood flow continued to decrease, while the outer layer of blood stasis. These findings essentially negate the accepted view of renal end-myeloid shunts over the years. This article on the anatomy of medulla blood circulation