目的:探讨医院超说明书用药管理及药学服务模式,对超说明书用药进行规范管理,促进临床合理用药。方法:对肾内科、风湿免疫科、肿瘤科、儿科和皮肤科5个科室超说明书用药进行管理,并进行分级管理。对临床应用普遍的且不良反应较小的药物论证超说明用药的可行性,如盐酸氨溴索注射液雾化吸入;对不良反应较大的药物,回顾性调查研究用药规范性及不良反应情况,如环磷酰胺。结果:初步建立超说明书用药管理模式和流程及药学服务模式。为超说明书用药管理提供参考。结论:通过超说明书用药管理及药学服务,可以规范用药,促进合理用药。 OBJECTIVE: To explore the management and pharmacy service mode of super manual in hospital and to regulate the administration of super manual and promote the rational use of clinical medicine. Methods: The Department of Nephrology, Rheumatology, Oncology, Pediatrics and dermatology superfamily 5 sections of the medication management, and hierarchical management. The clinical application of common and less adverse drug demonstration demonstrated the feasibility of medication, such as ambroxol hydrochloride injection inhalation; for the adverse reactions of larger drugs, retrospective study of drug use norms and adverse reactions , Such as cyclophosphamide. Results: The initial instructions to establish super-drug management mode and process and pharmacy service model. For super manual drug administration provide a reference. Conclusion: Through super manual drug administration and pharmacy services, we can standardize medication and promote rational drug use.