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将 6 5例确诊为肾综合征出血热 (HFRS)的住院患者列为观察组 ,选 10例正常者作为对照组。监测 HFRS患者各期的空腹血糖、血淀粉酶、脂肪酶及胰岛素含量 ,并随机选出 30例 HFRS患者 ,于发热末期或少尿期行口服葡萄糖耐量试验及胰岛素释放试验 (口服 75 g糖 )。发现 HFRS患者在发热期即出现血糖、血淀粉酶、脂肪酶及胰岛素水平升高、服糖后胰岛素释放减少、糖耐量减低。此变化在少尿期最显著 ,多尿期次之 ,恢复期渐正常 ,极重型、重型者较中型、轻型者变化更显著 ,说明 HFRS患者胰腺功能损害与病程进展及轻重相一致 ,检测胰腺功能有助于 HFRS的早期诊断和病情判断。在治疗中输糖时应给予适量胰岛素 ,以促进糖的利用 ,防治糖代谢紊乱
Sixty-five inpatients diagnosed with hemorrhagic fever with renal syndrome (HFRS) were enrolled in the observation group, and 10 normal subjects were selected as the control group. Fasting blood glucose, blood amylase, lipase and insulin content were monitored in all stages of HFRS patients. Thirty HFRS patients were randomly selected. Oral glucose tolerance test and insulin release test (oral administration of 75 g of sugar) were performed at the end of fever or oliguria. . HFRS patients found that blood glucose during the fever, blood amylase, lipase and insulin levels increased, decreased insulin release after administration of glucose, impaired glucose tolerance. This change in the oliguria period the most significant, followed by polyuria, the recovery period as normal, very heavy, heavy type than the medium, light changes were more significant, indicating that patients with impaired pancreatic function in HFRS progress and severity of the disease consistent with the detection of the pancreas Function contributes to the early diagnosis and condition judgment of HFRS. In the treatment of sugar should be given appropriate amount of insulin to promote the use of sugar, prevention and treatment of glucose metabolism disorder