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作者将MRI同血清学、微细胆管造影和组织学表现联系起来,旨在研究Gd-EOB-DTPA(钆-乙氧基苯-二乙烯二胺戊乙酸)显示急性和慢性、选择性和完全性胆汁瘀积的生物学行为和诊断价值,并推测其在肝胆的分泌机制。①动物模型:对44只约300g的Wistar雄性鼠进行麻醉[肌注氟丁酰酮(1.0ml/kg)、氯氨酮盐酸化物(0.5ml/kg)和二甲苯吡啶盐酸化物(0.5ml/kg)〕以及剖腹术。动物分3组:组1为选择性胆管梗阻(SBO),20只,解剖分离右肝管和尾
The authors linked MRI with serology, microchromatography and histological findings to study the acute and chronic, selective, and complete Gd-EOB-DTPA (gadolinium-ethoxybenzene-diethylenediaminepentaacetic acid) Cholestasis of biological behavior and diagnostic value, and speculated that the secretion of hepatobiliary mechanism. Animal Models: Forty-four Wistar male rats, weighing about 300 g, were anesthetized with ketorolac (1.0 ml / kg), ketamine hydrochloride (0.5 ml / kg) and xylene pyridine hydrochloride (0.5 ml / kg)] and laparotomy. Animals were divided into 3 groups: Group 1 was choledocholithiasis (SBO), 20 were dissected and the right hepatic duct and tail were dissected