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应用免疫组织化学方法检测p53蛋白、peNA和SI00蛋白在恶性黑色素瘤（简称恶黑）和黑色素清（简称黑德）组织中的表达，并探讨在临床和病理方面的意义。三材料与方法本院病理科自1980年一lops年收到恶黑及黑病各12例，将保存蜡块重新切片进行P53蛋白和peNA的免疫组化检测。试剂
Immunohistochemistry was used to detect the expression of p53 protein, peNA, and SI00 protein in malignant melanoma (abbreviated as black) and melanin clear (abbreviated as Heide) tissues, and to explore the clinical and pathological significance. Three Materials and Methods Our hospital pathology department received 12 cases of schizophrenia and black disease in each lops year in 1980. The preserved wax pieces were re-sectioned for immunohistochemical detection of P53 protein and peNA. Reagent