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研究酸枣仁散的药效学作用。观察酸枣仁散对小鼠自主活动、协同戊巴比妥钠对小鼠睡眠作用的影响,以及对小鼠耐缺氧能力、耐高温能力和镇痛作用的影响。结果与对照组相比,酸枣仁散可以显著减少小鼠自主活动次数;明显增加戊巴比妥钠致小鼠睡眠时间;显著提高小鼠耐缺氧能力;可提高小鼠的耐高温能力;镇痛效果不明显。结论:酸枣仁散有较好的镇静、催眠、耐缺氧功效。酸枣仁散作为新型饲料添加剂应用于中兽医临床提供实验依据。
Study on the pharmacodynamics of Suanzaoren Powder. To observe the effect of Suanzaoren Powder on mice’s autonomic activity and the synergetic effect of sodium pentobarbital on the mice’s sleep function, as well as their hypoxia tolerance, high temperature tolerance and analgesic effect. Results Compared with the control group, Suanzaoren Powder can significantly reduce the frequency of spontaneous activity in mice; significantly increase the sleep time of mice induced by pentobarbital sodium; significantly improve the hypoxia tolerance ability of mice; enhance the ability of high temperature resistance in mice; Analgesic effect is not obvious. Conclusion: Suanzaoren Powder has a better sedation, hypnosis, hypoxia tolerance effect. Suanzaoren powder as a new feed additive used in veterinary medicine to provide experimental evidence.