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肾病综合征(NS)患者的血栓发生率约8～33％。通常认为这种现象是凝血及纤溶的失衡所致。主要表现为与血小板高凝聚有关的促凝物质Ⅰ、Ⅴ、Ⅷ因子增加和某些血凝抑制物 ATⅢ减少。为此,作者对64例 NS病人的促凝系统、抑制系统及血小板凝聚功能进行了前瞻性研究。本研究64例患者皆具备血清白蛋白浓度<30g/L和尿蛋白排泄>3.0g/24h。其中原发肾病综合征36例,继发性者28例。6例发现血栓栓塞。根据有无血栓栓塞、膜性肾病、ATⅢ和血清白蛋白水平将64例NS 病人分组作了生物资料与血栓栓塞发生率的相关
Thrombosis in patients with nephrotic syndrome (NS) is about 8 to 33%. This phenomenon is usually thought of as an imbalance between coagulation and fibrinolysis. Mainly for platelet hypercoagulation related to procoagulant substance Ⅰ, Ⅴ, Ⅷ factor increased and some hemostatic inhibitor AT Ⅲ decreased. To this end, the authors of 64 cases of NS patients procoagulant system, inhibition and platelet aggregation function of a prospective study. All 64 patients in this study had serum albumin concentration <30g / L and urinary protein excretion> 3.0g / 24h. Of which 36 cases of primary nephrotic syndrome, secondary to 28 cases. 6 cases found thromboembolism. According to the presence or absence of thromboembolism, membranous nephropathy, AT Ⅲ and serum albumin levels, 64 patients with NS were divided into groups for biological data and incidence of thromboembolism