据报告克罗恩病病人有较高的骨质疏松流 行率。鉴于长期患克罗恩病病人常与脂溶性维生素(包括维生素K)缺乏相关,维生素K是骨钙素羧化的辅助因子,故高水平循环未羧化骨钙素也是维生素K缺乏的敏感指标。本研究旨在评估克罗恩病病人血清和骨中维生素K状况,并确定其与骨矿物质密度(BMD)的关系。 Crohn’s disease patients are reported to have a higher prevalence of osteoporosis. In view of the long-term suffering from Crohn’s disease patients often associated with the lack of fat-soluble vitamins (including vitamin K), vitamin K is a cofactor for osteocalcin carboxylation, so high levels of circulating non-carboxylated osteocalcin is also a sensitive indicator of vitamin K deficiency . The purpose of this study was to evaluate the status of vitamin K in serum and bone of patients with Crohn’s disease and to determine their association with bone mineral density (BMD).