血栓和出血一直是导致缺血性心脏病、中风和创伤性损伤的最大致命因素,因此及时的诊断、疾病风险的管理和抗血栓或抗凝血治疗的监测就变得尤为重要。传统的凝血试验有部分活化凝血酶原时间(APTT)、活化凝血酶原时间/INR(PT/INR)和血小板聚集功能试验等。APTT、PT能有效的反映凝血的级联过程因而在全球范围内得以广泛应用,而且已经成为了食品与药物管理局 Thrombosis and hemorrhage have been the single most devastating causes of ischemic heart disease, stroke and traumatic injury, so timely diagnosis, management of disease risk, and monitoring of antithrombotic or anticoagulant therapy become particularly important. Traditional coagulation tests have partial activated prothrombin time (APTT), activated prothrombin time / INR (PT / INR) and platelet aggregation function test. APTT, PT can effectively reflect the coagulation cascade process and thus widely used around the world, and has become the Food and Drug Administration