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目的观察小儿重症支原体肺炎使用不同剂量甲泼尼龙琥珀酸钠(甲强龙)治疗的临床效果。方法选取医院就诊住院的重症支原体肺炎患儿48例,随机分为试验组和对照组,每组24例。对照组采用甲强龙静脉注射,每天1次,每次剂量2mg/kg;试验组采用甲强龙静脉注射,每天2次,每次剂量2mg/kg。观察2组患者在1个疗程内病情发展的情况。结果试验组治疗总有效率为83.3%,高于对照组的66.7%,差异有统计学意义(P<0.05)。结论使用较大剂量甲强龙对于小儿重症支原体肺炎的治疗效果显著,值得推广使用。
Objective To observe the clinical effect of using different doses of methylprednisolone succinate (methylprednisolone) in children with severe mycoplasma pneumonia. Methods Forty-eight children with severe mycoplasma pneumonia admitted to hospital were randomly divided into experimental group and control group, with 24 cases in each group. The control group was treated with methylprednisolone once a day for 2mg / kg. The experimental group was treated with methylprednisolone twice a day for 2mg / kg. Two groups of patients were observed within 1 course of disease progression. Results The total effective rate of the experimental group was 83.3%, which was higher than that of the control group (66.7%), the difference was statistically significant (P <0.05). Conclusion The use of larger doses of methylprednisolone has a significant therapeutic effect on pediatric severe mycoplasma pneumonia and is worth promoting.