慢性阻塞性肺疾病(chronic obstructive pulmonary dis- ease,COPD)是一组以进行性气流受限为特征的疾病,在全球范围内的发病率不断上升。如患者出现症状加重和(或)需要增加药物治疗,称为COPD急性加重(acute exacerbation of COPD,AECOPD)。此时病情复杂,支气管-肺部感染、气道阻塞、呼吸肌疲劳、多脏器功能不全等交错存在。这些多方面的 Chronic obstructive pulmonary disease (COPD) is a group of diseases characterized by progressive airflow limitation, and the incidence is on a global scale. If the patient exacerbates the symptoms and / or requires additional medications, it is called acute exacerbation of COPD (AECOPD). At this point the condition is complicated, bronchus - pulmonary infection, airway obstruction, respiratory muscle fatigue, multiple organ dysfunction and other staggered existence. These are many