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目的研究广西藤茶提取物APS在体外对乙肝病毒(HBV)的作用。方法采用血清药理学方法,将APS含药血清作用于2.2.15细胞,收集细胞上清液,用MTT法测定细胞上清液中HBsAg、HBeAg的含量。结果APS含药血清对2.2.15细胞分泌的HBsAg、HBeAg有显著抑制作用。结论APS对2.2.15细胞分泌乙型肝炎病毒抗原有抑制作用。
Objective To study the effect of Guangxi A. vine tea extract APS on hepatitis B virus (HBV) in vitro. Methods Serum pharmacological methods were used to treat APS drug-containing serum in 2.2.15 cells. Cell supernatant was collected and the content of HBsAg and HBeAg in the cell supernatant was determined by MTT assay. Results APS-containing serum significantly inhibited the secretion of HBsAg and HBeAg in 2.2.15 cells. Conclusion APS inhibits the secretion of hepatitis B virus antigen from 2.2.15 cells.