论文部分内容阅读
目的探讨母乳瘦素对新生儿体格发育的影响。方法选择2007年1月至2009年6月在本院顺产的健康产妇及其新生儿各120名,根据喂养方式分为纯母乳喂养组、混合喂养组和纯配方奶喂养组,测定分娩时脐血及产后第3、28天新生儿血清和母乳瘦素水平,测量新生儿出生时、生后28天体重和身长,并计算Ponderal指数(PI),比较各组瘦素变化及新生儿体格发育情况,探讨二者之间的关系。结果各组新生儿血清瘦素水平出生时差异无统计学意义(P>0.05),第3天纯配方奶组低于纯母乳组[(1.7±1.2)μg/L比(2.6±1.4)μg/L,P<0.05],第28天纯配方奶组低于纯母乳组和混合喂养组[(2.3±1.1)μg/L比(3.2±1.3)μg/L、(2.9±1.4)μg/L,P均<0.05]。新生儿出生时各组PI值差异无统计学意义(P>0.05),第28天纯配方奶组高于纯母乳组和混合喂养组[(2.9±0.3)g/cm3比(2.7±0.2)g/cm3、(2.8±0.3)g/cm3,P均<0.05]。产妇母乳瘦素水平第3天各组差异无统计学意义(P>0.05),第28天混合组低于纯母乳组[(11.7±3.8)μg/L比(13.5±4.6)μg/L,P<0.05]。结论不同喂养方式影响新生儿瘦素水平,并进而影响新生儿期体格发育,母乳瘦素是新生儿瘦素的主要来源。
Objective To investigate the effect of breast milk leptin on the physical development of neonates. Methods A total of 120 healthy mothers and their newborns were randomly selected from January 2007 to June 2009 in our hospital. According to the method of feeding, we divided them into exclusive breastfeeding group, mixed feeding group and pure formula feeding group. The navel Blood and postpartum neonatal serum and lactalbumin levels were measured on the 3rd and 28th day postpartum. Body weight and body length at birth were measured at 28th day after birth. Ponderal index (PI) was calculated. Leptin level in each group and physical development in newborn Situation, explore the relationship between the two. Results There was no significant difference in the serum leptin level at birth between the three groups (P> 0.05). On the third day, the serum level of leptin in the pure milk group was lower than that of the pure milk group [(1.7 ± 1.2) μg / L vs (2.6 ± 1.4) μg /L,P<0.05]. On the 28th day, the pure formula group was lower than the pure breast milk group and the mixed group [(2.3 ± 1.1) μg / L vs (3.2 ± 1.3) μg / L, (2.9 ± 1.4) μg / L, P <0.05]. There was no significant difference in PI at birth among the newborns (P> 0.05). On the 28th day, the pure milk formula group was higher than the pure milk and mixed feeding group (2.9 ± 0.3) g / cm3 (2.7 ± 0.2) g / cm3, (2.8 ± 0.3) g / cm3, P <0.05]. There was no significant difference in the level of maternal leptin between the three groups on the third day (P> 0.05). On the 28th day, the mixed group was lower than the pure breast milk group (11.7 ± 3.8μg / L vs 13.5 ± 4.6μg / L, P <0.05]. Conclusion Different feeding modes affect the level of leptin in newborns, and further affect the physical development during neonatal period. Leptin in breast milk is the main source of leptin in newborns.