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目的;观察221例头痛症患者“微斯卡胶囊”治疗前后的微循环和血液流变学变化。方法:将头痛症病人分成两组,第一组为治疗前或未经治疗组,另一组为药物“微斯卡胶囊”治疗21天或42天组;观察指标包括微血管直径,微血流速度,红细胞聚集,血液粘度,红细胞变形性等。结果:未经治疗组的微循环和血液流变学有较严重的病理改变,如微血管收缩,血流变慢,红细胞发生聚集,血液粘度升高,红细胞变形性降低;“微斯卡”治疗以后,大多数病人的症状明显减轻或消失,微循环和血液流变学有了很大改善,上述指标恢复如正常对照组水平。结论:“微斯卡胶囊”治疗头痛是有效的;微循环和血液流变学指标用于疾病诊断和药物疗效观察有积极和广泛的作用。
Objectives; To observe the changes of microcirculation and hemorheology before and after treatment of 221 cases of headache patients with “Weasca capsules”. Methods: The patients with headache were divided into two groups. The first group was treated with or without treatment, and the other group was treated with “Weisca capsule” for 21 days or 42 days. The observation indexes included microvessel diameter, Speed, erythrocyte aggregation, blood viscosity, erythrocyte deformability and the like. Results: In the untreated group, microcirculation and hemorheology had more serious pathological changes such as microvascular contraction, slow blood flow, aggregation of erythrocytes, increase of blood viscosity and decrease of erythrocyte deformability. After the majority of patients significantly reduced or disappeared symptoms, microcirculation and hemorheology has been greatly improved, the above indicators recovery as the normal control group. Conclusion: Weisca capsule is effective in treating headache. Microcirculation and hemorheology indexes have a positive and extensive role in the diagnosis of disease and the observation of therapeutic effect.