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目的研究胺碘酮联合131I治疗伴发房颤的G raves病的疗效。方法48例伴发房颤的G raves病患者随机分为两组,每组各24例,131I治疗后2天分别给予胺碘酮和心得安,观察131I治疗后15 d、30 d、90 d的FT3、FT4水平和脉搏次数及房颤例数。结果131I联合胺碘酮组15 d、30 d后的FT3、FT4水平较131I联合心得安组显著降低(P<0.05),房颤人数显著减少(P<0.05)。结论胺碘酮联合131I治疗伴发房颤的G raves病有较好的疗效。
Objective To study the efficacy of amiodarone combined with 131I in the treatment of G raves disease with atrial fibrillation. Methods 48 patients with G raves disease accompanied with atrial fibrillation were randomly divided into two groups, 24 cases in each group. Amiodarone and propranolol were administered to the rats in each group 2 days after 131I treatment. The effects of 131I on the 15 d, 30 d, 90 d FT3, FT4 levels and pulse frequency and atrial fibrillation cases. Results The levels of FT3 and FT4 in 131I combined with amiodarone group decreased significantly (P <0.05) and the number of atrial fibrillation decreased significantly (P <0.05) after 131 d and amiodarone group for 30 days. Conclusion Amiodarone combined with 131I treatment of G raves disease associated with atrial fibrillation has a good effect.