目前,临床上使用的新药越来越多,很多新药的不良反应、配伍禁忌等在药物说明书中尚未详细说明,因对新药的了解不全面或使用不当,在使用过程中易出现一些配伍变化。伊立替康(irinotecan)是喜树碱类细胞毒药物中新上市的药物之一,有S期特异性细胞杀伤作用,具有广谱的抗肿瘤活性,被认为是近年来最有前途的抗癌药物之一。目前伊立替康、氟尿嘧啶(fluorouracil)、亚叶酸钙(calcium folinatc)联合 At present, more and more new drugs are used clinically, many adverse reactions of new drugs, incompatibility of compatibility, etc. have not been described in detail in the drug specification. Because of incomplete or improper understanding of new drugs, some compatibility changes tend to occur during use. Irinotecan, one of the newly marketed drugs in camptothecins, has S-phase specific cytotoxicity and broad spectrum anti-tumor activity and is considered as the most promising anti-cancer drug in recent years One of the medicines. Currently irinotecan, fluorouracil (fluorouracil), calcium folinatc