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目的:探讨颞肌外钛网修补颅骨缺损的临床疗效。方法:回顾性分析定远县总医院2013年3月至2018年12月收治的颅骨缺损患者48例的临床资料，患者均行颞肌外钛网修补术治疗，对临床疗效、预后及并发症发生情况进行分析。结果:48例患者中，临床一期愈合44例，癫痫发作2例，硬膜外血肿1例，钛网外露1例。结论:颞肌外钛网修补颅骨缺损，颅骨塑形满意，具有较高的临床价值，术前充分准备，严格无菌、规范操作，有助于减少术后并发症，进一步提高手术疗效。“,”Objective:To explore the clinical effect of cranioplasty with titanium mesh outside temporal muscle on skull defect.Methods:The clinical data of 48 patients with skull defect admitted to the General Hospital of Dingyuan County from March 2013 to December 2018 were retrospectively analyzed.All patients received cranioplasty with titanium mesh outside temporal muscle, and the clinical efficacy, prognosis and complications were analyzed.Results:Of the 48 cases, there were 44 cases of clinical primary healing, 2 cases of epileptic seizure, 1 case of epidural hematoma and 1 case of titanium mesh exposure.Conclusion:Skull defect repaired with titanium mesh outside temporal muscle, the skull is satisfied in shape and it has high clinical value.In order to reduce the postoperative complications and improve the surgical efficacy, fully prepared before operation, strict aseptic and standardized operation are must.