论文部分内容阅读
目的探讨脾错构瘤的临床病理特征、免疫表型及鉴别诊断。方法报道1例脾错构瘤的临床病理和免疫组化,结合文献对该肿瘤的临床病理学特征、诊断与鉴别诊断进行讨论。结果脾错构瘤常偶然发现。肿块境界清,由随意排列的血管腔隙构成,腔内衬窦内皮细胞,宽的髓索样间隔中富于网状纤维,散在间质细胞、淋巴细胞和嗜酸性粒细胞浸润。免疫组化示CD31(+),CD34(-)/CD8(+)。结论脾错构瘤为罕见的良性肿瘤,明确诊断须结合临床、组织学及免疫组化标记。
Objective To investigate the clinicopathological features, immunophenotype and differential diagnosis of splenic hamartoma. Methods One case of spleen hamartoma was identified by clinicopathological and immunohistochemical methods. The clinicopathological features, diagnosis and differential diagnosis of the tumor were discussed in the literature. Results spleen hamartoma often found by chance. The lumps of the tumor were clear and consisted of randomly arranged vascular cavities. Endovascular sinus endothelial cells were lined with wide cytoplastic fibers interspersed with interstitial cells, lymphocytes and eosinophils. Immunohistochemistry showed CD31 (+), CD34 (-) / CD8 (+). Conclusions Spleen hamartoma is a rare benign tumor. The diagnosis should be combined with clinical, histological and immunohistochemical markers.