用等电聚焦（ＩＥＦ）法初步分析了４例献血员丙型肝炎病毒（ＨＣＶ）感染血清。结果表明：ＨＣＶ感染血清显示３６条蛋白带，其中ｐＩ６．５和ｐＩ６．９带较正常血清着色为深，ｐＩ８．８、ｐＩ８．９和ｐＩ９．０带为明显的特征带。提示ＩＥＦ法对于ＨＣＶ隐性感染诊断可能具有重要的实际应用价值 Four isolates of hepatitis C virus (HCV) infection were analyzed by isoelectric focusing (IEF). The results showed that there were 36 protein bands in HCV-infected sera, in which pI6.5 and pI6.9 belonged to darker than normal serum, and pI8.8, pI8.9 and pI9.0 belonged to obvious bands. It is suggested that the IEF method may have important practical value for the diagnosis of latent infection of HCV