采用正交设计 ,以柴胡皂苷A ,芍药苷 ,橙皮苷 ,甘草酸四种指标成分为指标 ,考察了药材粒度、加水量、提取时间等工艺条件 ,并对醇沉、超滤及大孔树脂吸附三种分离精制方法进行了成分及药效学比较 ,结果大孔树脂吸附法精制效果最好 Orthogonal design was used to evaluate the process parameters such as particle size, water addition, and extraction time of four ingredients of Saikosaponin A, Paeoniflorin, Hesperidin and Glycyrrhizic acid, and alcohol precipitation, ultrafiltration and large Porous resin adsorption three kinds of separation and purification methods for the comparison of ingredients and pharmacodynamics, the results of macroporous resin adsorption refining the best