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目的观察慢性阻塞性肺疾病(COPD)患者采用双水平气道正压通气(BiPAP)治疗的临床效果。方法将76例COPD患者按照患者入院就诊顺序随机分为试验组和对照组各38例。对照组仅采用常规治疗措施,试验组在常规治疗同时配合Bi PAP治疗。比较2组患者治疗前后二氧化碳分压(PaCO_2)、pH值、心率(HR)、血氧分压(PaO_2)、第1秒用力肺活量/用力肺活量(FEV1/FVC)、呼吸频率(RR)以及血氧饱和度(SaO_2)等各项指标变化情况。结果治疗后2组患者的pH、PaO_2、SaO_2及FEV1/FVC均高于治疗前,PaCO_2、RR及HR均低于治疗前,且试验组变化幅度大于对照组,差异均有统计学意义(P<0.05)。结论 COPD患者采用Bi PAP治疗的临床效果良好,可有效改善患者的临床症状,可在临床上广泛推广。
Objective To observe the clinical effect of bi-level positive airway pressure (BiPAP) in patients with chronic obstructive pulmonary disease (COPD). Methods Seventy-six patients with COPD were randomly divided into experimental group and control group according to the order of admission. The control group only used conventional treatment, the experimental group in the conventional treatment combined with Bi PAP treatment. The PaCO 2, pH, heart rate (PaO 2), FEV 1 / FVC, respiration rate (RR) and blood (blood pressure) were compared between the two groups before and after treatment Oxygen saturation (SaO_2) and other indicators of changes. Results The pH, PaO 2, SaO 2 and FEV 1 / FVC of the two groups after treatment were higher than before treatment, PaCO 2, RR and HR were lower than before treatment, and the changes in the experimental group were greater than those in the control group (P <0.05). Conclusion The clinical effect of Bi PAP in patients with COPD is good, which can effectively improve the clinical symptoms of patients and can be widely used clinically.