论文部分内容阅读
目的 探讨简化吸入丙酸氟替卡松治疗哮喘的应用方法。方法 对 3 0例符合哮喘的患者 ,随机对照分为高剂量组 16例 ,低剂量组 14例。选用丙酸氟替卡松连续治疗 12周 ,比较治疗前后病情、肺功能变化。结果 高剂量组治疗后轻、中、重度患者的肺功能 (FEV1、PEF)较治疗前有明显提高 (P <0 0 1) ,低剂量组FEV1无明显提高 (P >0 0 5 ) ,PEF有明显提高 (P <0 0 1) ,两组治疗后比较差异无显著性 (P >0 0 5 ) ;高剂量组和低剂量组的症状、病情较治疗前都有明显好转 (均P <0 0 1) ,两组间差异无显著性 (P >0 0 5 )。两组病情的严重程度与高、低剂量没有明显关系 (P >0 0 5 )。结论 根据哮喘患者的病情严重程度采用高、低剂量的方案治疗哮喘可有效地控制哮喘 ,而且实用简便易行。
Objective To explore the method of simplifying inhalation of fluticasone propionate in the treatment of asthma. Methods Thirty patients with asthma were randomly divided into high dose group (n = 16) and low dose group (n = 14). Fluticasone propionate continuous treatment for 12 weeks, comparing the condition before and after treatment, pulmonary function changes. Results The lung function (FEV1, PEF) in high, moderate and severe group was significantly higher than that before treatment (P <0.01), but not in low dose group (P> 0.05). The PEF (P <0.01). There was no significant difference between the two groups after treatment (P> 0.05). The symptom and condition of high dose group and low dose group were significantly improved (all P < There was no significant difference between the two groups (P> 0.05). There was no significant relationship between the severity of the two groups and the high and low doses (P> 0.05). Conclusion The treatment of asthma based on the severity of asthma patients with high and low doses of asthma can be effective in controlling asthma, and practical and easy.