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慢性乙型肝炎是由乙型肝炎病毒感染引起的,乙型肝炎病毒的复制使肝细胞持续慢性损伤,致细胞外基质可逆性沉积,导致肝纤维化,甚至演变为肝硬化[1]。脂肪肝的发病机制是胰岛素抵抗等初次打击导致肝细胞脂肪变性,氧应激、脂质过氧化损伤等二次打击诱发肝细胞坏死和炎症浸润,进而激活肝星状细胞诱发肝纤维化,最终可导致肝硬化和肝细胞癌,还能促进心脑血管事件的发生。因此,治疗慢性乙型肝炎合
Chronic hepatitis B is caused by Hepatitis B virus infection. Hepatitis B virus replication causes chronic damage to hepatocytes, resulting in the reversible deposition of extracellular matrix, leading to liver fibrosis and even cirrhosis [1]. The pathogenesis of fatty liver is initial attack of insulin resistance, which leads to hepatic steatosis and inflammatory infiltration caused by secondary shock of hepatic steatosis, oxygen stress and lipid peroxidation injury, and then activation of hepatic stellate cells to induce hepatic fibrosis. Finally, Can lead to cirrhosis and hepatocellular carcinoma, but also to promote the occurrence of cardiovascular and cerebrovascular events. Therefore, the treatment of chronic Hepatitis B cohabitation