免疫基因治疗已成为癌症治疗的一种新疗法。它是用基因修饰的肿瘤细胞刺激抗肿瘤的特异免疫性,导致肿瘤排斥的主动免疫疗法。这种经基因操作的肿瘤细胞具有直接或(和)间接两种作用。直接作用为免疫调节分子对靶细胞的溶解或向上的调节作用,间接作用为效应免疫细胞在肿瘤部位的募集反 Immune gene therapy has become a new treatment for cancer treatment. It is the use of genetically modified tumor cells to stimulate specific anti-tumor immunity, leading to active immunotherapy of tumor rejection. This genetically manipulated tumor cell has direct or (and) indirect effects. The direct effect is the regulation of the lysis or upregulation of the immune regulatory molecules on the target cells, and the indirect effect is the recruitment of the effector immune cells on the tumor site.