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目的:研究2型糖尿病(DM)患者脉压(PP)大小与其血管病变的相关性。方法:以145例2型DM患者为研究对象,根据PP水平分为A组[PP<60mmHg(1mmHg=0.133kPa)],B组(PP≥60mmHg)。比较2组患者冠状动脉病变积分、血β2-微球蛋白、尿β2-微球蛋白的差异。结果:2组患者相比:B组冠状动脉病变积分、血β2-微球蛋白、尿β2-微球蛋白显著高于A组(P<0.01)。logistic逐步回归分析发现PP是冠状动脉病变积分、血β2-微球蛋白、尿β2-微球蛋白的独立危险因素。结论:PP是预测2型DM患者血管病变严重程度的参考指标。
Objective: To study the relationship between pulse pressure (PP) and vascular lesions in type 2 diabetes mellitus (DM). Methods: One hundred and forty-five patients with type 2 DM were divided into group A (PP <60mmHg (1mmHg = 0.133kPa)] and group B (PP≥60mmHg). The differences of coronary artery disease, blood β2-microglobulin and urinary β2-microglobulin between the two groups were compared. Results: Compared with group B, coronary artery lesion score, blood β2-microglobulin and urinary β2-microglobulin in group B were significantly higher than those in group A (P <0.01). Logistic stepwise regression analysis found that PP was an independent risk factor for coronary artery disease, blood β2-microglobulin and urinary β2-microglobulin. Conclusion: PP is a reference index for predicting the severity of vascular lesions in type 2 DM patients.