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《New Scientist》1983;97(1345):440。在肿瘤处于最早期,也就是细胞在出现异常之前,利用一种新技术很快就能检出肿瘤。伦敦伊莉沙白皇后学院的细胞生物学家Andrew Sincock等能在熟练的病理学家发现细胞内结构异常之前的数月甚至数年,鉴别出宫颈涂片中致癌的潜在性恶性细胞。此种新的、半自动式试验能够使大规模宫颈癌检查计划较为经济。癌细胞的DNA与稀释的酸接触后呈现易感性,因此,可对潜在的癌细胞进行鉴别。DNA短暂暴露于酸后,吸收了试验板上一定
New Scientist 1983; 97 (1345): 440. Before the tumor is at its earliest stage, that is, before the cells become abnormal, tumors can be detected quickly using a new technique. Andrew Sincock, a cell biologist at Queen Elizabeth University in London, could identify potentially carcinogenic malignant cells in cervical smears months and even years before skilled pathologists discovered intracellular structural abnormalities. This new, semi-automated test can make a large-scale cervical cancer screening program more economical. Cancer cells’ DNA is susceptible to contact with diluted acids, and therefore potential cancer cells can be identified. DNA was briefly exposed to acid and absorbed on the assay plate