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目的探讨更年期功能性子宫出血的临床特点与治疗方法和效果。方法更年期功能性子宫出血40例随机分为2组,对照组20例采用传统药物治疗,治疗组20例在此基础上加用复方醋酸棉酚治疗。结果经过治疗后,治疗组总有效率90.0%,对照组总有效率70.0%。治疗组疗效明显好于对照组(P<0.05)。治疗前两组ER与PR比较差异无统计学意义(P>0.05),两组用药后ER与PR的平均水平较用药前明显下降(P<0.05),同时治疗组的下降幅度明显高于对照组(P<0.05)。两组40例患者在服药期间未出现明显不良反应,具有较高的安全性,两组不良反应情况相比差异无统计学意义(P>0.05)。结论更年期功能性子宫出血临床发病复杂,常规药物配伍复方醋酸棉酚治疗更年期功能性子宫出血效果好,可有效改善孕激素水平,安全性强,值得推广应用。
Objective To investigate the clinical features, treatment and efficacy of functional uterine bleeding in menopause. Methods 40 cases of menopausal functional uterine bleeding were randomly divided into two groups, the control group of 20 patients treated with traditional drugs, the treatment group of 20 patients on the basis of this compound plus acetate acetate treatment. Results After treatment, the total effective rate was 90.0% in the treatment group and 70.0% in the control group. The treatment group was significantly better than the control group (P <0.05). There was no significant difference between PR and PR before treatment (P> 0.05). The average level of ER and PR after treatment in both groups was significantly lower than that before treatment (P <0.05), and the decrease of ER and PR in treatment group was significantly higher than that in control group Group (P <0.05). There were no significant adverse reactions in the 40 patients in the two groups during the medication period, with high safety. There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusions Clinical onset of menopausal functional uterine bleeding is complicated. Conventional drug combination with compound gingivalisil is effective in treating menopausal functional uterine bleeding, which can effectively improve the progesterone level, which is safe and worthy of promotion.