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目的探讨硫辛酸联合神经愈痹液腿浴治疗糖尿病周围神经病变的临床疗效。方法将2013-12~2015-05本院收治的90例糖尿病周围神经病变患者随机分为硫辛酸组(30例)、腿浴组(30例)和联合组(30例),采用相应的方法进行治疗,比较2周后3组临床疗效。结果联合组总有效率(80.0%)明显高于硫辛酸组(50.0%)和腿浴组(46.7%)(P<0.05);3组治疗后运动和感觉神经传导速度较治疗前均明显升高,且硫辛酸组和腿浴组治疗后运动和感觉神经传导速度均明显低于联合组治疗后(P<0.05)。结论硫辛酸联合神经愈痹液腿浴治疗糖尿病周围神经病变有助于改善临床症状,促进运动和感觉神经传导速度恢复,可在临床上推广应用。
Objective To investigate the clinical efficacy of lipoic acid combined with neurovascular therapy in the treatment of diabetic peripheral neuropathy. Methods Ninety patients with diabetic peripheral neuropathy admitted to our hospital from December 2013 to May 2015 were randomly divided into three groups: lipoic acid group (30 cases), leg bath group (30 cases) and combination group (30 cases) For treatment, compared 3 weeks after 2 weeks of clinical efficacy. Results The total effective rate (80.0%) in the combination group was significantly higher than that in the lipoic acid group (50.0%) and the leg bath group (46.7%) (P <0.05). The motor and sensory nerve conduction velocity were significantly increased High, and lipoic acid group and leg bath group after exercise and sensory nerve conduction velocity were significantly lower than the combined group after treatment (P <0.05). Conclusions Lipoic acid combined with neuromuscular blockade therapy in the treatment of diabetic peripheral neuropathy can improve clinical symptoms and promote the recovery of motor and sensory nerve conduction velocity and can be widely applied in clinic.