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目的 :比较胰酶胶囊与多酶片治疗胰腺炎伴消化不良病人的疗效。方法 :将 63例病人随机分成 2组 ,胰酶胶囊组 33例给予胰酶胶囊 2粒 ,po ,tid× 4wk ;多酶片组 30例给予多酶片 5片 ,po ,tid× 4wk ;服药后 2 ,4wk进行临床症状的积分评价。结果 :胰酶胶囊组治疗 2wk后在腹痛、饱胀、胃肠胀气、腹泻等积分分别下降了 (0 .86± 0 .13)分 ,(1.33± 0 .14 )分 ,(1.4 0± 0 .2 1)分 ,(0 .90± 0 .16)分 ;多酶片组分别下降了 (0 .13± 0 .0 3)分 ,(0 .37±0 .0 4 )分 ,(0 .36± 0 .0 7)分 ,(0 .15± 0 .0 4 )分。均P<0 .0 1。治疗后 4wk胰酶胶囊组总有效率为94 %、多酶片组为 5 7% ,2组间比较P <0 .0 5。结论 :胰酶胶囊治疗胰腺炎伴消化不良症状的疗效明显优于多酶片
Objective: To compare the efficacy of pancreatin capsule and multi-enzyme tablet in the treatment of patients with pancreatitis and dyspepsia. Methods: Sixty-three patients were randomly divided into two groups. Pancreatic enzyme capsule group (33 cases) was given pancreatin capsule (2 capsules), po, tid × 4wk. After 2, 4wk clinical symptom score evaluation. Results: The score of abdominal pain, fullness, flatulence, diarrhea and other integrals of pancreatin capsule group decreased by (0.86 ± 0.13) points, (1.33 ± 0.14) points, (1.4 ± 0) points (0.90 ± 0.16) points in the multi-enzyme tablets group, (0.13 ± 0.30) points, (0.37 ± 0.04) points and (0 .36 ± 0 .0 7) points, (0 .15 ± 0. 0 4) points. All P <0 .0 1. The total effective rate of 4wk pancreatin capsule group after treatment was 94% and that of multi-enzyme tablet group was 57%, P <0.05. Conclusion: The effect of pancreatin capsule in treating pancreatitis with dyspeptic symptoms is obviously better than that of multi-enzyme tablets