随着医药工业的发展 ,越来越多的化学药品不断问世 ,药物的疗效越来越好 ,但药物的不良反应也日益增加。据有关资料统计 ,药物不良反应约占全部住院原因的 5% ,住院病人中药物不良反应发生率约占 10～ 2 0 % [1] 。而且 ,由于肝脏在药物代谢中起重要作用 ,是药物浓集、转化、代 With the development of the pharmaceutical industry, more and more chemicals are coming out constantly, and the efficacy of the drugs is getting better and better, but the adverse reactions of the drugs are also increasing day by day. According to statistics, adverse drug reactions accounted for about 5% of all hospitalized patients, hospitalized patients with adverse drug reactions accounted for about 10 ~ 20% [1]. Moreover, since the liver plays an important role in drug metabolism, it is drug concentration, transformation, generation