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癫痫是神经内科临床中十分常见的病症类型,小儿癫痫的发病原因、病症表现和治疗措施均与成年人有所不同,抗癫痫药物的药代动力学特点也与成年人有明显,癫痫的发作和抗癫痫药物的应用对患者的正常发育、学习和生活均造成较大的影响。传统临床中应用的抗癫痫药物副作用明显,患儿不易耐受。随着医学中对癫痫的深入研究以及抗癫痫药物的更新换代,小儿难治性癫痫的临床治疗取得显著进步。本文通过对儿童难治性癫痫的研究并结合文献资料针对儿童难治性癫痫的治疗进展作一综述。
Epilepsy is a very common clinical type of neurology, the incidence of pediatric epilepsy, symptoms and treatment measures are different with adults, anti-epileptic drugs pharmacokinetic characteristics are also obvious with adults, epileptic seizures And antiepileptic drugs on the patient’s normal development, learning and living have a greater impact. The traditional clinical application of antiepileptic drugs obvious side effects, difficult to tolerate children. With the in-depth study of epilepsy in medicine and the replacement of antiepileptic drugs, clinical treatment of refractory epilepsy in children has made significant progress. This article reviews the research progress of refractory epilepsy in children and the progress of the treatment of refractory epilepsy in children with literature data.