患者童××,27岁,已婚未孕,继发性闭经2年,于1989年12月8日入院。既往月经正常,自1988年1月起闭经并发现乳房逐渐萎缩,下腹汗毛增多,声音变低沉,曾多次使用克罗米芬、HCG及中药治疗无效。经用人工周期疗法后,月经来潮。体检:头顶部呈O型脱发,面部有少数痤疮,喉结轻度隆起,双侧乳房平坦,腹中线及小腿汗毛又长又密。妇检:外阴阴毛呈男性棱形分布,阴蒂明显增大3×2×0.7cm,两侧小阴唇较肥大。阴道及宫 Childhood × ×, 27 years old, married and not pregnant, secondary amenorrhea for 2 years, on December 8, 1989 admitted. Previous normal menstruation, since January 1988 amenorrhea and found that the gradual decline of the breast, lower abdomen increased hair, the sound becomes low, had repeatedly use clomiphene, HCG and Chinese medicine treatment is invalid. After using artificial cycle therapy, menstrual cramps. Physical examination: the top of the head was O-type hair loss, a small number of facial acne, mild drooping Adam’s apple, bilateral breast flat, midline and calf hair long and dense. Women’s examination: male genital pubic hair was prismatic distribution, clitoris significantly increased 3 × 2 × 0.7cm, both sides of the labia majora than hypertrophy. Vagina and Palace