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目的 探讨精浆 Ｚｎ 与 Ｃｕ Ｚｎ － Ｓ Ｏ Ｄ 之间的关系， Ｃｕ Ｚｎ － Ｓ Ｏ Ｄ 对慢性细菌性前列腺炎的影响，以及氧自由基在慢性细菌性前列腺炎中的作用。方法 采用电位溶出法和放射免疫分析法，测定了７１ 例慢性细菌性前列腺炎患者和２７９ 例非慢性细菌性前列腺炎男性精浆 Ｚｎ 和 Ｃｕ Ｚｎ － Ｓ Ｏ Ｄ 的含量。结果 慢性细菌性前列腺炎组精浆 Ｚｎ 和 Ｃｕ Ｚｎ － Ｓ Ｏ Ｄ 含量较对照组明显降低（ Ｐ＜ ０００１） ，精浆 Ｚｎ 和 Ｃｕ Ｚｎ － Ｓ Ｏ Ｄ 含量间存在显著正相关（ Ｐ＜ ０００１） ，且前列腺液 Ｗ Ｂ Ｃ 与精浆 Ｚｎ 和 Ｃｕ Ｚｎ － Ｓ Ｏ Ｄ 含量均呈负相关（ Ｐ＜ ００１） 。结论 慢性细菌性前列腺炎患者精浆 Ｚｎ 和 Ｃｕ Ｚｎ － Ｓ Ｏ Ｄ 含量下降，间接表明氧自由基与慢性细菌性前列腺炎有关。
Objective To investigate the relationship between Zn and Cu Zn - S O D, the effect of Cu Zn - S O D on chronic bacterial prostatitis and the role of oxygen free radicals in chronic bacterial prostatitis. Methods The contents of Zn and Cu Zn - S O D in seminal plasma of 71 patients with chronic bacterial prostatitis and 279 semen of non - chronic bacterial prostatitis were determined by potentiometry and radioimmunoassay. Results The contents of Zn and Cu Zn - S O D in seminal plasma of patients with chronic bacterial prostatitis were significantly lower than those of the control group (P <0001), and there was a significant positive correlation between the contents of Zn and Cu Zn - S O D in seminal plasma (P < 0001), and the prostatic fluid W B C was negatively correlated with the content of Zn and Cu Zn - S O D in seminal fluid (P <001). Conclusion The content of Zn and Cu Zn - S O D in seminal fluid of patients with chronic bacterial prostatitis is decreased, which indirectly indicates that oxygen free radical is associated with chronic bacterial prostatitis.