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目的 :比较萘普生与赖氨匹林治疗小儿发热的疗效。方法 :萘普生组 10 0例 (男性 60例 ,女性40例 ;年龄 4.5a±s 2 .8a) ,给萘普生片剂 8～ 10mg/(kg·次 ) ,最大量 0 .2 5 g/次 ,po ;赖氨匹林对照组 30例 (男性 16例 ,女性 14例 ;年龄 3.9a± 2 .4a)给赖氨匹林针剂 10～ 2 5mg/(kg·次 ) ,im ;2组均于用药 1次后观察疗效。结果 :2组用药 0 .5h体温降至 <38℃ ,分别占 5 %与 33% ,用药 2h分别占8 %与 97% (P >0 .0 5 ) ,维持疗效时间分别为 9.0h± 2 .0h与 5 .0h± 1.0h(P <0 .0 1)。结论 :2药均为较好解热药 ,萘普生维持疗效时间长于赖氨匹林
OBJECTIVE: To compare the efficacy of naproxen and meticlopram in the treatment of pediatric fever. Methods: 100 cases of naproxen group (male 60, female 40; age 4.5a ± s 2 .8a), naproxen tablets 8 ~ 10mg / (kg · times), the maximum amount of 0.52 g / second, po; Limalepirin control group of 30 patients (16 males and 14 females; age 3.9a ± 2. .4a) to give lysophilin injection 10 ~ 25mg / (kg · times), im; 2 groups were observed after treatment effect. Results: The body temperature of the two groups were decreased to <38 ℃ at 5h and then decreased to 38 ℃, accounting for 5% and 33%, respectively. The duration of treatment was 9.0h ± 2 .0h and 5.0h ± 1.0h (P <0.01). Conclusion: The two drugs are better antipyretic drugs, naproxen maintenance effect longer than that of lysiplatin