应用免疫荧光技术极易检出免疫复合物介导的肾小球肾炎病人体内的免疫球蛋白和补体沉积物,然而要鉴定出形成免疫复合物的抗原还是一项十分艰难的工作。在人类某些类型的肾小球肾炎中,引起肾炎的免疫复合物的形成与内源性抗原(核抗原、肾小球基底膜抗原、肿瘤抗原和免疫球蛋白抗原)有关。 Using immunofluorescence technology is extremely easy to detect immunoglobulins and complement deposits in immune complex-mediated glomerulonephritis patients. However, identifying antigen that forms immune complexes is still a very difficult task. In some human forms of glomerulonephritis, the formation of immune complexes that cause nephritis is associated with endogenous antigens (nuclear antigens, glomerular basement membrane antigens, tumor antigens and immunoglobulin antigens).