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目的:探讨颞骨炎性肌纤维母细胞瘤的临床表现,术中所见,以及组织病理学特征。方法:结合文献复习,报告1例颞骨炎性肌纤维母细胞瘤患者的临床资料并行光镜检查和免疫组织化学染色分析。结果:肿瘤呈侵袭性生长,有明显的骨质吸收、破坏。病理组织学检查主要由梭形细胞和大量炎症细胞构成。免疫组织化学显示波形蛋白、平滑肌特异性肌动蛋白以及CD68均为阳性,S-100、CK均为阴性。结论:颞骨炎性肌纤维母细胞瘤是一种少见的呈侵袭性生长的肿瘤,容易局部复发。治疗以手术为主,辅以激素治疗。
Objective: To investigate the clinical manifestations, intraoperative findings and histopathological features of temporal bone myoblatoma. Methods: According to the literature review, one case of temporal bone myoblatoma was analyzed by light microscopy and immunohistochemical staining. Results: The tumors showed aggressive growth with obvious bone absorption and destruction. Histopathological examination is mainly composed of spindle cells and a large number of inflammatory cells. Immunohistochemistry showed that vimentin, smooth muscle-specific actin and CD68 were positive, S-100, CK were negative. Conclusion: The temporal bone myoblastoma is a rare invasive tumor that grows easily with local recurrence. Surgical treatment-based, supplemented by hormone therapy.