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目的探讨糖类抗原199(CA199)在卵巢良性畸胎瘤诊断中的临床意义。方法选取2005年4月至2011年4月太仓市中医医院妇产科进行手术治疗并术前行CA199在内的4种肿瘤标记物检测且术后经病理证实为良性畸胎瘤患者68例,对其临床资料进行回顾性分析。结果在4种肿瘤标记物中,CA199的阳性率最高,为33.8%。肿瘤最大径线平均大小为(6.21±3.12)cm。CA199、CA125升高组肿瘤大于正常组(P<0.05);当肿瘤发生于双侧卵巢时,CA199显著升高(P<0.05);患者平均年龄36.7岁,年龄小者CA199阳性率高于年龄大者。结论 CA199在卵巢良性畸胎瘤的诊断和鉴别诊断中具有一定意义。当血清CA199升高时,无论对侧卵巢是否正常,手术时均应仔细检查对侧卵巢。
Objective To investigate the clinical significance of carbohydrate antigen 199 (CA199) in the diagnosis of benign ovarian teratoma. Methods From April 2005 to April 2011, 68 patients with benign teratoma confirmed by pathology were enrolled in this study. Four kinds of tumor markers such as CA199, which were surgically treated in Department of Obstetrics and Gynecology, Taicang Hospital of TCM, The clinical data were retrospectively analyzed. Results Of the four tumor markers, CA199 had the highest positive rate of 33.8%. The average diameter of the largest tumor line was (6.21 ± 3.12) cm. CA199, CA125 elevated group of tumors than normal group (P <0.05); CA199 was significantly increased (P <0.05) when the tumor occurred in bilateral ovaries; the average age of patients was 36.7 years old, the younger the CA199 positive rate was higher than the age Big person Conclusion CA199 has certain significance in the diagnosis and differential diagnosis of benign ovarian teratoma. When the serum CA199 increased, regardless of the contralateral ovary is normal, the contralateral ovary should be carefully examined during surgery.