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从百合科鬚瓣开口箭的根茎分得开口箭素。呈强心甙顏色化学反应。由蛙腿淋巴囊給药,能使蛙心停止于收縮期。在位兔心試驗,靜脉注射1.2毫克/公斤后增大心动振幅,继而呈現心收縮不規则,30分钟后使心跳停止。按Langendorff法制备离体兔及豚鼠心脏,用1:10~5溶液灌注,初期振幅增大,继而节律不整,20—30分钟后心脏停止于收縮或舒张状态。对猫及脉鼠均产生典型的洋地黄样心电图改变:使P—R,R—R间期延长、T波压低或倒置。按照中国药典規定測定其鸽的最小致死量为:1.394±0.069毫克/公斤。其生物活性大于黄花夹竹桃甙(thevetin),而小于g-毒毛旋花子甙。
Divided from the rhizome of the Lilium divaricate flap arrows open aperture element. Was cardiac glycosides color chemical reaction. By the frog legs lymphatic sac, can make the frog heart stopped at systole. In a rabbit heart test, intravenous injection of 1.2 mg / kg increased cardiac amplitude, followed by an irregular heart contraction, 30 minutes after the heart rate to stop. The Langendorff method was used to prepare isolated rabbit and guinea pig heart. Perfused with 1:10 ~ 5 solution, the initial amplitude increased, then the rhythm became irregular. After 20-30 minutes, the heart stopped in systole or diastole. Cats and rats have a typical digitalis-like ECG changes: the P-R, R-R interval prolongation, T-wave pressure down or upside down. In accordance with the provisions of the Chinese Pharmacopoeia determination of the pigeons of the minimum lethal dose: 1.394 ± 0.069 mg / kg. Its biological activity is greater than the yellow oleander (thevetin), and less than g-toxin agouti.