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目的探讨联合测定血糖(GLU)、糖化血清蛋白(GSP)、糖化血红蛋白(HbAlc),在糖尿病患者血糖控制和治疗效果监测中的临床意义。方法选择符合糖尿病诊断标准的患者120例为观察组;另选择无其他内分泌代谢疾病的体格健康者100例为对照组。测定正常对照组和病例观察组观察对象的GLU、GSP、HbALc含量,并进行统计学比较和相关性分析。结果两组GLU、GSP、HbALc测定含量比较,差异有统计学意义(P<0.01),且三者之间具有正相关关系。结论联合测定和动态观察糖尿病患者GLU、GSP、HbALc含量,可为临床监测GLU控制状况和糖尿病治疗效果提供有价值的依据。
Objective To investigate the clinical significance of the combined measurement of GLU, GSP and HbAlc in the monitoring of glycemic control and therapeutic effect in diabetic patients. Methods One hundred and twenty patients who met the diagnostic criteria of diabetes were selected as the observation group. Another 100 healthy individuals who had no other endocrine and metabolic diseases were selected as the control group. The contents of GLU, GSP and HbALc in the normal control group and the case observation group were determined and compared statistically and correlation analysis. Results The contents of GLU, GSP and HbALc in the two groups were significantly different (P <0.01), and there was a positive correlation between them. Conclusion The combined determination and dynamic observation of GLU, GSP and HbALc levels in diabetic patients can provide valuable evidence for clinical monitoring of GLU control and diabetes treatment.