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目的探讨间质性膀胱炎的诊断与治疗。方法回顾性分析2002年7月—2004年6月诊治的10例间质性膀胱炎患者的临床资料。患者均为女性。平均年龄41岁;平均病程3.4年。符合美国国立糖尿病、消化和肾脏疾病学会间质性膀胱炎诊断标准。均行钾离子敏感试验,8例呈阳性反应。O′Leary Sant间质性膀胱炎症状评分9～20分,平均(14±4)分。所有病人首先行治疗性水扩张,1个月后评价疗效,对疗效不佳和水扩张后复发者行其他治疗。结果10例平均随访7.8个月。水扩张后1个月症状评分降至4～19分,平均(11±6)分,治疗前后比较,差异有统计学意义(t=4.394,P<0.05)。症状显著缓解2例,评分下降>7分;部分缓解3例,评分下降>3分。无效5例。有效率50%。结论钾离子敏感试验在间质性膀胱炎患者中有较高的阳性率。治疗性水扩张可作为首选的治疗方法。
Objective To investigate the diagnosis and treatment of interstitial cystitis. Methods The clinical data of 10 patients with interstitial cystitis who were diagnosed and treated from July 2002 to June 2004 were retrospectively analyzed. All patients were female. The average age of 41 years; average duration of 3.4 years. In line with the National Institute of Diabetes, Digestive and Kidney Diseases diagnostic criteria for interstitial cystitis. All patients underwent potassium ion sensitivity test, 8 cases were positive. O’Leary Sant interstitial cystitis symptom score of 9 to 20 points, an average of (14 ± 4) points. All patients first treated with therapeutic water expansion, evaluation of efficacy after 1 month, poor efficacy and recurrence of water after the expansion of other treatment. Results The average follow-up of 10 patients was 7.8 months. Symptom scores decreased from 4 to 19 points (mean, 11 ± 6) at 1 month after water expansion. There was a significant difference between before and after treatment (t = 4.394, P <0.05). Symptoms were significantly alleviated in 2 cases, the score decreased> 7 points; partial remission in 3 cases, the score decreased> 3 points. Invalid 5 cases. Effective rate of 50%. Conclusion Potassium sensitivity test has a high positive rate in patients with interstitial cystitis. Treatment of water expansion can be used as the preferred method of treatment.