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将连续培养的恶性疟原虫(P.f.)用不同药物处理48h是评价药物抗疟活性的标准方法,作者认为将体外条件调整到近似体内状况,将有助于了解现有抗疟药的药效动力学,以优化给药方案并增进对药物作用方式的认识。
The continuous culture of Plasmodium falciparum (Pf) treated with different drugs for 48h is the standard method to evaluate the anti-malarial activity of the drug. The author believes that the in vitro conditions adjusted to approximate the in vivo status, will help to understand the pharmacodynamic efficacy of existing anti-malarial drugs Learn to optimize dosing regimens and improve understanding of how drugs work.