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任何原因若长期持续损害肝脏,都将导致肝纤维化形成,其实质既是纤维结缔组织在肝中的异常增生和沉积,目前对肝纤维化的预防和治疗亦乏良策,本文对肝纤维化的一些新进展作一概述.肝纤维化的形成肝脏组织中结缔组织异常增生,原是对肝损害的修复反应,但增生过度,引起小叶结构紊乱、肝细胞功能受损、纤维间隔形成并发生门——肝静脉之间的吻合交通.遂形成门脉高压,这样便造成肝硬化的病理结果.肝脏结缔组织包括细胞成份及细胞外成份,细胞包括成纤维细胞及炎性免疫效应细胞(枯否氏细胞、淋巴细胞等),细胞外成份有:①胶原;②非
For any reason if long-term damage to the liver, will lead to the formation of liver fibrosis, its essence is both fibrous connective tissue in the liver abnormal proliferation and deposition, the current prevention and treatment of liver fibrosis is also a good strategy, this article on liver fibrosis Some of the new progress made an overview of the formation of liver fibrosis, abnormal growth of connective tissue in the liver, the original repair of liver damage response, but hyperplasia, causing lobular structure disorders, impaired liver cell function, the formation of fibrous septa and the door - Anastomosis between the hepatic veins Traffic is then made into portal hypertension, which results in the pathological result of cirrhosis Liver connective tissue includes cellular components and extracellular components including fibroblasts and inflammatory immune effector cells Cells, lymphocytes, etc.), extracellular components are: ① collagen; ② non