论文部分内容阅读
我们对肝脏隔离灌注技术三种不同灌注途径时肝组织与周围血中药物浓度的变化进行探讨。动物分为肝脏隔离灌注经门静脉灌注组，经肝动脉灌注组与经肝动脉门静脉联合灌注组。结果表明，肝脏隔离经门静脉灌组５－ＦＵ浓度肝组织中较高，明显优于经肝动脉灌注组，且术后肝功能变化轻微，无明显的肝细胞病理学变化，漏入周围血中的５－ＦＵ浓度亦相对较低。
We discuss the changes of drug concentration in liver tissue and peripheral blood in three different perfusion methods of liver isolation and perfusion. Animals were divided into hepatic segmental perfusion by portal vein perfusion group, the hepatic artery perfusion group and hepatic artery portal vein perfusion group. The results showed that hepatic isolation of 5-FU concentration in the portal vein group higher liver tissue was significantly better than the hepatic artery perfusion group, and postoperative changes in liver function slight, no significant changes in liver cell pathology, leaking into the peripheral blood The 5-FU concentration is also relatively low.